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Memory Becomes Less Efficient Very Early In Alzheimer's Disease

A new study has found that during a very early stage in Alzheimer's disease, people become less efficient at separating important information from less important information.

Knowing this, health practitioners may be able to train people in the early stages of Alzheimer's to remember high-value information more effectively. Understanding and maintaining important priorities is critical to functioning. Remembering what's most

The participants in the study were recruited from the Washington University in St. Louis Alzheimer's Disease Research Center. They included 109 healthy older adults (average age of almost 75), 41 people with very mild (very early) Alzheimer's disease (average age of almost 76), 13 people with mild (early) Alzheimer's (average age of almost 77), and 35 younger adults (all 25 or under, average age of almost 20.)

The researchers asked participants to study and learn neutral words that were randomly assigned different point values. When asked to recall the items, participants were asked to maximize the total value. All participants, even those with Alzheimer's, recalled more high-value than low-value items. However, the Alzheimer's groups were significantly less efficient than their healthy age peers at remembering items according to their value. Essentially, it meant they no longer maximized learning and memory, which in healthy people are fairly efficient processes.

The authors speculated that Alzheimer's disease makes it more difficult for people to encode what they learn in a strategic way. Because encoding is the first step in long-term memory, this affects their ability to remember things according to their value. The findings also demonstrate that value-directed learning stays intact in healthy aging. Older adults might not remember as much as younger adults, but when healthy, they remain able to distinguish what's important.

This research suggests the potential for improved memory training. People with early-stage Alzheimer's might remember important information better by learning to be more strategic and selective when encoding high-value information, even though it comes at the expense of neglecting less-important information, the researchers explained.

Journal reference:
Alan D. Castel, David A. Balota, and David P. McCabe. Memory Efficiency and the Strategic Control of Attention at Encoding: Impairments of Value-Directed
Remembering in Alzheimer's Disease. Neuropsychology, Vol. 23, No. 3

Editor's Note: This article is not intended to provide medical advice, diagnosis or treatment.

Administrator's Note: This article is reprinted here with the permission of Vitamin Power.